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Literature summary extracted from

  • Zeeuwen, P.L.; Cheng, T.; Schalkwijk, J.
    The biology of cystatin M/E and its cognate target proteases (2009), J. Invest. Dermatol., 129, 1327-1338.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.4.22.43 cystatin M/E high-affinity inhibitor of cathepsin V, directly controls the activity of cathepsin V Homo sapiens

Organism

EC Number Organism UniProt Comment Textmining
3.4.22.43 Homo sapiens
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.4.22.43 epidermis
-
 Homo sapiens
-
3.4.22.43 hair follicle in the root sheath of the hair follicles Homo sapiens
-
3.4.22.43 stratum granulosum
-
 Homo sapiens
-

Synonyms

EC Number Synonyms Comment Organism
3.4.22.43 CTSL2
-
 Homo sapiens
3.4.22.43 CTSV
-
 Homo sapiens
3.4.22.43 stratum corneum thiol protease
-
 Homo sapiens

Ki Value [mM]

EC Number Ki Value [mM] Ki Value maximum [mM] Inhibitor Comment Organism Structure
3.4.22.43 0.00000047
-
 cystatin M/E pH and temperature not specified in the publication Homo sapiens

General Information

EC Number General Information Comment Organism
3.4.22.43 physiological function CTSV is involved in the breakdown of corneodesmosomal proteins Homo sapiens